Solution  for  PRRS,  PMWS !!!


The environment friendly antibiotics
substitute Sol to Bio
was proved that it has remarkably powerful effect on
PMWS and PRRS through the cooperative research of
Junnam National University,Technology Centre
of Agriculture
& Forest Ministry and Seobong Biobestech.
 

SOL TO BIO

PROVED REMARKABLE EFFECT ON PRRS & PMWS


  Pigs were divided into two treatment of (1) Sol to Bio 0.3% group (2)
  Control group of No Sol to Bio group.
  After 2 weeks, pigs were inoculated with PCV-2 and PRRS virus.
  12 days later, pigs were slaughtered, and then virus were isolated
  from each organ and compared.

  As a result, in Sol to Bio group, remarkably much less PCV-2 virus
  were detected from Bronchial lymph node,
  Tonsil and Inguinal lymph node.
  PRRS virus from Lungs, Bronchial lymph node, Tonsil and Thymus.

  From 1g of Lung, 900K of PRRS virus were detected in No Sol to Bio
  group, but only 10K were detected in Sol to Bio 0.3% group
  In No Sol to Bio group, 9,000K of PCV-2 virus were detected
  from 1g of Bronchial lymph node,
  but only 6K virus were detected in Sol to Bio 0.3% group.
 
 

 

 Sol to Bio Experiment Result

  I. PMWS Experiment

  Methods and Results

Pigs were divided into two treatment of (1) Sol to Bio 0.3% group that Sol to Bio 0.3% was feed, (2) control group that Sol to Bio was not feed. After 2 weeks, pigs were inoculated with PCV-2 that is the cause-body of PMWS. After 12 days pigs were slaughtered, and then virus were isolated from each organ and compared. As a result, in Sol to Bio group, remarkably much less virus was detected from Bronchial lymph node, Tonsil and Inguinal lymph node those are the major contagion organ of PCV-2. Therefore, it can be concluded that feeding of Sol to Bio remarkably and significantly controls the multiplication of PCV-2 that is the cause-body of PMWS in pigs.

  Chart for Sol to Bio – PCV2 experiment in pig (Real time PCR)


Figure 1. Concentration of PCV-2  in different treatment of pigs after challenge 12 days

  Note: As log was used in the graph, there is remarkably big difference between two treatments.

  For example, in Bronchial lymph node, 9,000,000 copies/g of PCV-2 were detected from No Sol to Bio group, but only 6,000 copies/g of PCV-2 were detected from Sol to Bio 0.3% group.

 

  II. PRRS Experiment

  Methods and Results

Pigs were divided into two treatment of (1) Sol to Bio 0. group that Sol to Bio 0.3% was feed, (2) control group that Sol to Bio was not feed. After 2 weeks, pigs were inoculated with PRRS virus. After 12 days pigs were slaughtered, and then virus were isolated from each organ and compared. As a result, in Sol to Bio group, remarkably much less virus was detected from Lungs, Bronchial lymph node, Tonsil and Thymus. Therefore, it can be concluded that feeding of Sol to Bio remarkably and significantly controls the multiplication of PRRS virus in pigs.

  Chart for Sol to Bio – PRRS experiment in pig (plaque assay)


Figure 2a. Concentration of PRRS  in different treatment of pigs after challenge 12 days

  Note: For example, in Lungs, 900,000 pfu/g of PRRS were detected from No Sol to Bio group, but only 10,000 pfu/g of PRRS were detected from Sol to Bio 0.3% group.

 

  III. Conclusion

  According to above experiments, it is conclude that Sol to Bio remarkably controls the multiplication of PMWS and PRRS, and can be expected that Sol to Bio will be very helpful for prevention and reduction of viral diseases.

  Note: At these experiments, Sol to Bio was feed only for 26 days, but if feeding lead time increases, naturally the effect of controlling virus would be more powerful.